Simultaneous Determination of Hydrochlorothiazide and Benazepril Hydrochloride or Amiloride Hydrochloride in Presence of Hydrochlorothiazide Impurities: Chlorothiazide and Salamide by HPTLC Method
نویسندگان
چکیده
منابع مشابه
Simultaneous determination of hydrochlorothiazide and benazepril hydrochloride or amiloride hydrochloride in presence of hydrochlorothiazide impurities: chlorothiazide and salamide by HPTLC method.
Simple, selective and sensitive high-performance thin layer chromatographic (HPTLC) method has been developed and validated for the simultaneous determination of hydrochlorothiazide (HCZ) in the presence of its impurities (chlorothiazide (CT) and salamide (DSA)), in two quaternary mixtures with benazepril hydrochloride (BZ) or amiloride hydrochloride (AM). The separation was carried out on HPTL...
متن کاملValidated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form
Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F(254) plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods.
متن کاملSimultaneous Determination of Losartan and Hydrochlorothiazide in Pharmaceutical Preparations by Derivative and Ratio Derivative Spectrophotometry
Background & Aims: Losartan is a non-peptide potent antihypertensive agent that acts through blocking angiotensin II receptors. Hyzaar® is a combination product that contains two drugs, losartan and hydrochlorothiazide, used to lower high blood pressure. There are some reports regarding simultaneous measurement of the drugs in pharmaceutical and biological samples which includes HPLC, CE, CEC, ...
متن کاملSimultaneous quantification of nebivolol hydrochloride and hydrochlorothiazide by first derivative UV- Spectroscopy
A new sensitive, simple, rapid, accurate and precise method for simultaneous quantification of nebivolol HCl (NEB) and hydrochlorothiazide (HCT) in combined tablet dosage form has been developed. The method is based on the derivative spectrophotometric method at zero-crossing wavelengths. Two wavelengths 280nm (zero crossing point for NEB) and 272.2nm (zero crossing point for HCT) were selected...
متن کاملBenazepril plus amlodipine or hydrochlorothiazide for hypertension.
To the Editor: In their report on the Avoiding Cardiovascular Events through Combination Ther apy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial, Jamerson et al. (Dec. 4 is sue)1 challenge current treatment recommenda tions for hypertension. In the study, they report ed that the use of combined therapy with an angiotensinconverting–enzyme (ACE) inhibitor, benazepril, plus...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2014
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/bmu016